{"id":316,"date":"2021-04-26T20:08:38","date_gmt":"2021-04-26T18:08:38","guid":{"rendered":"https:\/\/www.bmag.cz\/?p=316"},"modified":"2024-05-27T20:40:18","modified_gmt":"2024-05-27T18:40:18","slug":"mali-pomocnici-s-velkym-ucinkem-pro-vyvazenou-strevni-floru","status":"publish","type":"post","link":"https:\/\/bmag.cz\/?p=316","title":{"rendered":"Mal\u00ed pomocn\u00edci s velk\u00fdm \u00fa\u010dinkem pro vyv\u00e1\u017eenou st\u0159evn\u00ed fl\u00f3ru"},"content":{"rendered":"\n

Tak, jako jin\u00e9 \u017eivo\u010dichy, jsme i my lid\u00e9, hostiteli \u0161irok\u00e9ho spektra bakteri\u00ed, pl\u00edsn\u00ed, parazit\u016f a vir\u016f, s nimi\u017e v\u0161ak \u017eijeme v symbi\u00f3ze<\/p>\n\n\n\n

Pro\u010d je zdrav\u00ed st\u0159evn\u00ed mikrofl\u00f3ry, odborn\u011b naz\u00fdvan\u00e9 tak\u00e9 st\u0159evn\u00ed mikrobiota, d\u016fle\u017eit\u00e9?<\/p>\n\n\n\n

Odpov\u011bdi nab\u00edz\u00ed MUDr. Iveta \u010cern\u00e1, PhD., D\u011btsk\u00e1 gastroenterologi\u010dkav DFNsP a hlavn\u00ed odbornice MZ \u010cR pro pediatrickou gastroenterologii, hepatologii a v\u00fd\u017eivu.<\/p>\n\n\n\n

Zvl\u00e1\u0161t\u011b dnes, kdy\u017e se p\u0159ed patogeny z vn\u011bj\u0161\u00edho prost\u0159ed\u00ed chr\u00e1n\u00edme, mo\u017en\u00e1 paradoxn\u011b vyzn\u00edv\u00e1 fakt, \u017ee jejich nezbytn\u011b pot\u0159ebujeme k \u017eivotu \u2026<\/p>\n\n\n\n

Lidsk\u00e9 t\u011blo je ide\u00e1ln\u00edm prost\u0159ed\u00edm pro dynamickou kolonizaci populace mikroorganism\u016f, kter\u00e9 se spole\u010dn\u011b naz\u00fdvaj\u00ed pojmem mikrobiota. Tyto mikroorganismy osidluj\u00ed nejen povrch na\u0161eho t\u011bla, ale i respira\u010dn\u00ed, urogenit\u00e1ln\u00ed a gastrointestin\u00e1ln\u00ed trakt a z toho je nejv\u00edce os\u00eddlen\u00e9 st\u0159evo. Lidsk\u00e9 st\u0159evo norm\u00e1ln\u011b obsahuje p\u0159ibli\u017en\u011b 1014 bakteri\u00e1ln\u00edch organism\u016f, 1000 r\u016fzn\u00fdch druh\u016f a celkov\u00fd po\u010det st\u0159evn\u00edch bakteri\u00ed je p\u0159ibli\u017en\u011b desetkr\u00e1t vy\u0161\u0161\u00ed ne\u017e po\u010det bun\u011bk lidsk\u00e9ho t\u011bla, p\u0159i\u010dem\u017e kolektivn\u00ed bakteri\u00e1ln\u00ed genom, nazvan\u00fd i mikrobi\u00f3m obsahuje 100kr\u00e1t v\u00edce gen\u016f jako cel\u00fd lidsk\u00fd genom.<\/p>\n\n\n\n

St\u0159evn\u00ed mikrobiota je dnes ozna\u010dov\u00e1na i za virtu\u00e1ln\u00ed org\u00e1n a tvo\u0159\u00ed slo\u017eit\u00fd komplex. Sv\u00e9 org\u00e1ny si ka\u017ed\u00fd um\u00ed z hodin biologie \u010di anatomie p\u0159edstavit a v\u00edme za co jsou ve fungov\u00e1n\u00ed organismu zodpov\u011bdn\u00e9. Jakou roli pro na\u0161e zdrav\u00ed m\u00e1 na\u0161e st\u0159evn\u00ed mikrofl\u00f3ra, resp. st\u0159evn\u00ed mikrobiota?<\/p>\n\n\n\n

M\u016f\u017eeme si ji skute\u010dn\u011b p\u0159edstavit jako virtu\u00e1ln\u00ed samostatn\u00fd org\u00e1n, kter\u00fd se pod\u00edl\u00ed na d\u016fle\u017eit\u00fdch metabolick\u00fdch a imunologick\u00fdch procesech, kter\u00e9 ovliv\u0148uj\u00ed organismus jako celek. Jej\u00ed spr\u00e1vn\u00e9 slo\u017een\u00ed ur\u010duje i zdravotn\u00ed stav jedince. Poru\u0161en\u00ed rovnov\u00e1\u017en\u00e9ho stavu st\u0159evn\u00ed mikrobioty a vznik tzv. dysbi\u00f3zy se d\u00e1v\u00e1 do souvislosti se vznikem r\u016fzn\u00fdch civiliza\u010dn\u00edch onemocn\u011bn\u00ed jako jsou diabetes, kardiovaskul\u00e1rn\u00ed onemocn\u011bn\u00ed, obezita, chronick\u00e9 z\u00e1n\u011bty st\u0159eva jako je Crohnova choroba, n\u00e1dorov\u00e1 a alergick\u00e1 onemocn\u011bn\u00ed.<\/p>\n\n\n\n

Co konkr\u00e9tn\u011b st\u0159evn\u00ed mikrobiotu tvo\u0159\u00ed a jak se b\u011bhem \u017eivota m\u011bn\u00ed?<\/p>\n\n\n\n

Slo\u017een\u00ed st\u0159evn\u00ed mikrobioty ovliv\u0148uj\u00ed r\u016fzn\u00e9 faktory, mezi nimi i v\u011bk a v\u00fd\u017eiva. St\u0159evn\u00ed mikrobi\u00f3m obsahuje velmi r\u016fznorodou a komplexn\u00ed komunitu mikroorganism\u016f ob\u00fdvaj\u00edc\u00edch st\u0159evn\u00ed trakt, kter\u00fd se b\u011bhem r\u016fzn\u00fdch f\u00e1z\u00ed \u017eivota m\u011bn\u00ed. N\u00e1\u0161 mikrobi\u00f3m proch\u00e1z\u00ed nejv\u00fdrazn\u011bj\u0161\u00edmi zm\u011bnami v d\u011btstv\u00ed a st\u00e1\u0159\u00ed. Jeho v\u00fdvoj za\u010d\u00edn\u00e1 bezprost\u0159edn\u011b po porodu a z\u00e1vis\u00ed na zp\u016fsobu porodu, v\u00fd\u017eivy novorozence a na okoln\u00edm prost\u0159ed\u00ed. Z\u00e1sadn\u00ed zlom nast\u00e1v\u00e1 po ukon\u010den\u00ed kojen\u00ed, kdy\u017e se v souvislosti se zm\u011bnou stravy za\u010dne podobat na st\u0159evn\u00ed fl\u00f3ru dosp\u011bl\u00e9. U zdrav\u00fdch jedinc\u016f je v pr\u016fb\u011bhu \u017eivota relativn\u011b stabiln\u00ed, a\u017e ve vy\u0161\u0161\u00edm v\u011bku doch\u00e1z\u00ed k jej\u00edmu v\u00fdrazn\u011bj\u0161\u00edm zm\u011bn\u00e1m.<\/p>\n\n\n\n

Co ovliv\u0148uje zdrav\u00ed na\u0161eho st\u0159evn\u00edho mikrobi\u00f3mu?<\/p>\n\n\n\n

V\u00fdznamnou funkci ve formov\u00e1n\u00ed st\u0159evn\u00edho mikrobi\u00f3mu m\u00e1 v\u00fd\u017eiva. Kontrolovan\u00e1 studie zkoumaj\u00edc\u00ed \u00fa\u010dinky diety na mikrobi\u00f3m uk\u00e1zala, \u017ee slo\u017een\u00ed st\u0159evn\u00ed mikrofl\u00f3ry se dramaticky m\u011bn\u00ed zv\u00fd\u0161en\u00fdm obsahem tuk\u016f ve strav\u011b a sn\u00ed\u017een\u00edm obsahu vl\u00e1kniny. „Westerniz\u00e1cia“ stravovac\u00edch n\u00e1vyk\u016f (pozn. Stravov\u00e1n\u00ed podle vzoru z\u00e1padn\u00edch zem\u00ed), vysok\u00e1 konzumace fastfood\u016f, slazen\u00fdch n\u00e1poj\u016f, rafinovan\u00fdch cukr\u016f a n\u00edzk\u00e1 konzumace vl\u00e1kniny se odr\u00e1\u017e\u00ed i na nep\u0159\u00edzniv\u00e9m, ne\u017e\u00e1douc\u00edm slo\u017een\u00ed st\u0159evn\u00edho mikrobi\u00f3mu. Jedn\u00edm z rizikov\u00fdch faktor\u016f je i vysok\u00e1 spot\u0159eba antibiotik.<\/p>\n\n\n\n

Pokud se chceme dob\u0159e starat o kvalitu na\u0161eho zdrav\u00ed, d\u00e1 se v\u011bdom\u011b p\u0159\u00edzniv\u011b ovlivnit i slo\u017een\u00ed na\u0161eho st\u0159evn\u00edho mikrobi\u00f3mu?<\/p>\n\n\n\n

Jednou z mo\u017enost\u00ed jak p\u0159\u00edzniv\u011b ovlivnit slo\u017een\u00ed st\u0159evn\u00edho mikrobi\u00f3mu jsou i probiotika. Podle definice FAO \/ WHO: „Probiotika jsou \u017eiv\u00e9 mikroorganismy, kter\u00e9 pokud se pod\u00e1vaj\u00ed v dostate\u010dn\u00e9m mno\u017estv\u00ed, maj\u00ed prokazateln\u011b pozitivn\u00ed \u00fa\u010dinek na zdrav\u00ed hostitele \/ p\u0159\u00edjemce“. (FAO: Food and Agriculture Organisation, WHO: World Health Organisation). Probiotika p\u016fsob\u00ed cestou \u00fapravy dysbi\u00f3zy, tedy potla\u010den\u00edm nep\u0159\u00edzniv\u00fdch kmen\u016f bakteri\u00ed a stabilizac\u00ed imunologick\u00e9 bari\u00e9ry ve sliznici tr\u00e1vic\u00edho traktu.<\/p>\n\n\n\n

Sta\u010d\u00ed konzumovat dostatek probiotick\u00fdch potravin nebo je d\u016fle\u017eit\u00e9 dod\u00e1vat probiotick\u00e9 kultury t\u011blu i jin\u00fdm zp\u016fsobem? A jak se vyznat v sou\u010dasn\u00e9 \u0161irok\u00e9 nab\u00eddce probiotik?<\/p>\n\n\n

\n
\"\"<\/figure>\n<\/div>\n\n\n

Nen\u00ed probiotikum jako probiotikum. Nesta\u010d\u00ed, \u017ee pacient si vybere z velk\u00e9 nab\u00eddky probiotik v l\u00e9k\u00e1rn\u011b, kter\u00e9 maj\u00ed zaru\u010den\u00fd efekt na v\u0161echny nemoci. Ka\u017ed\u00e9 probiotikum, ka\u017ed\u00fd jednotliv\u00fd kmen m\u00e1 sv\u00e9 specifick\u00e9 \u00fa\u010dinky a uplat\u0148uje se v \u0159e\u0161en\u00ed r\u016fzn\u00fdch zdravotn\u00edch probl\u00e9m\u016f, z nich\u017e jsou nej\u010dast\u011bji r\u016fzn\u00e9 gastrointestin\u00e1ln\u00ed pot\u00ed\u017ee jako jsou pr\u016fjmy, z\u00e1cpa, nad\u00fdm\u00e1n\u00ed, poruchy motility st\u0159eva apod. V\u00fdb\u011bru jednotliv\u00fdch vhodn\u00fdch kmen\u016f p\u0159i konkr\u00e9tn\u00edch pot\u00ed\u017e\u00edch p\u0159edch\u00e1z\u00ed mno\u017estv\u00ed studi\u00ed, kter\u00e9 potvrzuj\u00ed jejich p\u0159\u00edzniv\u00fd efekt.<\/p>\n\n\n\n

Pomozte va\u0161\u00ed st\u0159evn\u00ed mikrobiote!<\/p>\n\n\n\n

Pokud trp\u00edte nad\u00fdm\u00e1n\u00edm, pr\u016fjmem, z\u00e1cpou \u010di jin\u00fdm tr\u00e1vic\u00edm diskomfortem, pr\u00e1v\u011b pro v\u00e1s je ur\u010dena novinka na trhu – OsmobioticFlora.<\/p>\n\n\n\n

\n\n\n\n

Tip redakce: Zdrav\u00ed<\/a> je to nejd\u016fle\u017eit\u011bj\u0161\u00ed co m\u00e1me, na\u010derpejte inspiraci jak se o sv\u00e9 zdrav\u00ed spr\u00e1vn\u011b starat.<\/p>\n\n\n\n

\n","protected":false},"excerpt":{"rendered":"

Tak, jako jin\u00e9 \u017eivo\u010dichy, jsme i my lid\u00e9, hostiteli \u0161irok\u00e9ho spektra bakteri\u00ed, pl\u00edsn\u00ed, parazit\u016f a vir\u016f, s nimi\u017e v\u0161ak \u017eijeme v symbi\u00f3ze Pro\u010d je zdrav\u00ed st\u0159evn\u00ed mikrofl\u00f3ry, odborn\u011b naz\u00fdvan\u00e9 tak\u00e9 st\u0159evn\u00ed mikrobiota, d\u016fle\u017eit\u00e9? Odpov\u011bdi nab\u00edz\u00ed MUDr. Iveta \u010cern\u00e1, PhD., D\u011btsk\u00e1 gastroenterologi\u010dkav DFNsP a hlavn\u00ed odbornice MZ \u010cR pro pediatrickou gastroenterologii, hepatologii a v\u00fd\u017eivu. Zvl\u00e1\u0161t\u011b dnes, […]<\/p>\n","protected":false},"author":2,"featured_media":317,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"tdm_status":"","tdm_grid_status":"","footnotes":""},"categories":[1],"tags":[],"class_list":["post-316","post","type-post","status-publish","format-standard","has-post-thumbnail","category-rady-a-navody"],"amp_enabled":true,"_links":{"self":[{"href":"https:\/\/bmag.cz\/index.php?rest_route=\/wp\/v2\/posts\/316","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/bmag.cz\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/bmag.cz\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/bmag.cz\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/bmag.cz\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=316"}],"version-history":[{"count":1,"href":"https:\/\/bmag.cz\/index.php?rest_route=\/wp\/v2\/posts\/316\/revisions"}],"predecessor-version":[{"id":713,"href":"https:\/\/bmag.cz\/index.php?rest_route=\/wp\/v2\/posts\/316\/revisions\/713"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/bmag.cz\/index.php?rest_route=\/wp\/v2\/media\/317"}],"wp:attachment":[{"href":"https:\/\/bmag.cz\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=316"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/bmag.cz\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=316"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/bmag.cz\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=316"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}